Dadeldhura district a part of Mahakali zone, is one of the seventy-five districts of Nepal, a landlocked country of South Asia. The district, with Dadeldhura as its district headquarters, covers an area of 1,538 km² and had a population of 126,162 in 2001 and 142,094 in 2011.

The region has a desert-mountainous landscape that contains many religious temples. The district is seldom visited by tourists but contains local routes to Mt Kailaish in Tibet, Ra Ra Lake in Humla district and the last remaining remnants of the Far Western Malla Kingdom. Nagi Malla was the last royal to live here before Nepalese unification.

The spoken language is Dadeldhuri and the majority of inhabitants are Hindu. The district is entirely rural and has yet to be modernized. The largest city is Dadheldura city.